Through games of Jan. 23, 2022:
| # | School (No. 1 votes) | W-L | Pts. | Prev. |
| 1 | Randolph-Macon (24) | 14-1 | 623 | 1 |
| 2 | Illinois Wesleyan | 14-2 | 577 | 3 |
| 3 | Washington U. | 14-1 | 566 | 4 |
| 4 | UW-Oshkosh | 15-2 | 542 | 5 |
| 5 | UW-Platteville | 17-1 | 526 | 2 |
| 6 | Marietta | 14-2 | 490 | 6 |
| 7 | Yeshiva | 14-1 | 447 | 7 |
| 8 | Christopher Newport (1) | 17-2 | 443 | 9 |
| 9 | St. Joseph (Conn.) | 13-0 | 440 | 8 |
| 10 | UW-La Crosse | 15-2 | 423 | 10 |
| 11 | Mount Union | 13-2 | 314 | 17 |
| 12 | Johns Hopkins | 13-2 | 307 | 13 |
| 13 | Maryville (Tenn.) | 14-1 | 303 | 16 |
| 14 | Williams | 14-1 | 236 | 20 |
| 15 | Swarthmore | 15-2 | 235 | 11 |
| 16 | Whitworth | 15-2 | 233 | 18 |
| 17 | WPI | 15-1 | 230 | 19 |
| 18 | Wheaton (Ill.) | 14-4 | 201 | 14 |
| 19 | Elmhurst | 12-4 | 181 | 12 |
| 20 | Wesleyan | 15-2 | 144 | 15 |
| 21 | Mary Hardin-Baylor | 13-2 | 114 | 22 |
| 22 | Oswego State | 15-1 | 112 | 25 |
| 23 | Augsburg | 14-2 | 93 | -- |
| 24 | Emory | 11-4 | 90 | -- |
| 25 | Nazareth | 14-1 | 41 | -- |
Dropped out: No. 21 Heidelberg; No. 23 RPI; No. 24 Case Western Reserve
Others receiving votes: Mass-Dartmouth 38; Heidelberg 37; DeSales 36; Case Western Reserve 32; LeTourneau 16; Berry 15; RPI 13; Middlebury 10; Wabash 5; Claremont-Mudd-Scripps 3; Keene State 3; Guilford 2; Tufts 2; Brandeis 1; Penn State-Harrisburg 1.
The D3hoops.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly. Points are awarded on a 25-24-23-22-etc. basis.